Timing of cognitive decline in CLN3 disease
نویسندگان
چکیده
منابع مشابه
Reversal of cognitive decline in Alzheimer's disease
Alzheimer's disease is one of the most significant healthcare problems nationally and globally. Recently, the first description of the reversal of cognitive decline in patients with early Alzheimer's disease or its precursors, MCI (mild cognitive impairment) and SCI (subjective cognitive impairment), was published [1]. The therapeutic approach used was programmatic and personalized rather than ...
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Azadvar M, Alizadeh HR, Najafinia M, Safarnejad MR and Esfandiari S (2019) Citrus sudden decline disease in the south of Kerman province. Plant Pathology Science 8(2): 31-37. DOI: 10.2982/PPS.8.2.31 During recent years, the newly emerging disease, citrus sudden decline (CSD) has destroyed many of citrus trees grafted onto bael rootstock in the south of Kerman Province. The disease is caus...
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Periodontitis is common in the elderly and may become more common in Alzheimer's disease because of a reduced ability to take care of oral hygiene as the disease progresses. Elevated antibodies to periodontal bacteria are associated with an increased systemic pro-inflammatory state. Elsewhere raised serum pro-inflammatory cytokines have been associated with an increased rate of cognitive declin...
متن کاملPreventing cognitive decline in preclinical Alzheimer's disease.
Alzheimer's disease (AD) is a chronic neurodegenerative disease leading to cognitive decline, dementia, and ultimately death. Despite extensive R&D efforts, there are no diseases modifying treatments for AD available. The stage in which patients receive a clinical diagnosis of probable AD may be too late for disease modifying pharmacotherapy. Prevention strategies may be required to successfull...
متن کاملCognitive decline in prodromal Alzheimer disease and mild cognitive impairment.
OBJECTIVE To characterize the course of cognitive decline during the prodromal phase of Alzheimer disease. DESIGN Longitudinal cohort study with up to 16 years of observation. PARTICIPANTS Older persons from 2 studies underwent annual clinical evaluations that included cognitive function testing and clinical classification of mild cognitive impairment, dementia, and Alzheimer disease. At ba...
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ژورنال
عنوان ژورنال: Journal of Inherited Metabolic Disease
سال: 2018
ISSN: 0141-8955,1573-2665
DOI: 10.1007/s10545-018-0143-x